My diet:
Comparison

Annatto vs Tartrazine

The short answer
Annatto is the better pick for most families: a seed extract with no warning label. Yellow 5 is brighter, cheaper and very stable, but EU packages must warn it may affect children's attention.
Side by sideAnnattoTartrazine (Yellow 5)
Safety score86/100 Generally safe40/100 Best to avoid
Made fromAchiote seeds ✓ BetterPetroleum-based synthesis
EU warning labelNot required ✓ BetterRequired
ShadeYellow to orangeBright lemon yellow
AllergiesRare reactions reportedRare reactions, more with aspirin sensitivity
Heat and light stabilityGoodVery stable ✓ Better
Safety score86 ✓ Better40

Swapping one for the other

Many US brands of mac and cheese and cheese crackers have already switched from Yellow 5 and Yellow 6 to annatto and paprika. Check the label for "annatto" or "colored with paprika."

Common questions

Is annatto a dye?

It's a natural color, extracted from seeds. In the US it's exempt from the certification required for synthetic dyes like Yellow 5.