My diet:
Comparison

Acesulfame Potassium vs Sucralose

The short answer
Sucralose tastes more like sugar; Ace-K has a slightly bitter finish on its own, which is why the two are often blended. For baking, Ace-K is the safer bet because sucralose can break down at high oven temperatures.
Side by sideAcesulfame Potassium (Ace-K)Sucralose (Splenda)
Safety score62/100 Use in moderation60/100 Use in moderation
Sweetness vs sugarAbout 200×About 600×
Taste on its ownSlightly bitter aftertasteClosest to sugar ✓ Better
Baking above 120 °CStable ✓ BetterCan break down into chlorinated compounds
Safe daily limit (EFSA)15 mg per kg15 mg per kg
Calories and blood sugarZero / noneZero / none
Safety score6260

Swapping one for the other

You'll rarely choose between them at the store: most diet sodas and "zero sugar" drinks use both. For home baking, consider erythritol, allulose or a stevia blend instead.

Common questions

Why are they used together?

Each one masks the other's aftertaste, and the blend tastes sweeter than either alone, so less of each is needed.