My diet:

Lactase (Beta-galactosidase)

No E-numberEnzymesOrigin: Fermented
Get a personal answer

Pick your family’s diets in the bar above.

Every diet

VeganYes

Made by fermentation, with no animal source.

Gluten-freeYes
HalalYes
KosherYes
KetoYes

No carbohydrate.

Low-FODMAPYes
The short answer
Lactase is the enzyme that breaks lactose into glucose and galactose, and it is what makes lactose-free milk possible. It is made by fermentation, so it is vegan, and it is safe for everyone including people who cannot digest lactose.
Generally safe

Fine for most people at normal amounts.

E-numberNone
Comes fromFermented
What it doesEnzymes
Glycemic index—
Daily limitNot set
Also calledLactase, Beta-galactosidase

Rules by country

🇺🇸 US FDAApproved
🇪🇺 European UnionApproved
🇨🇦 Health CanadaApproved
CaliforniaNo extra rules

Lactase is generally recognized as safe in the US, with FDA GRAS notices for beta-galactosidase enzyme preparations from several sources. In the EU it is a food enzyme authorized under the food enzymes regulation rather than an additive with an E-number, and it is permitted in Canada for the same purpose.

Daily limit: Experts haven’t set a number because normal food amounts are far below any level of concern.

What is it?

A cow's milk lactose molecule is a pair of sugars, and without the enzyme to split it the pair passes through the gut undigested, which is what causes the gas and discomfort. Lactase does that splitting before the milk reaches the gut. The enzyme is grown in a fermenter, usually from Kluyveromyces lactis or Aspergillus oryzae, and it is dosed in units of activity rather than in grams, so a tiny amount does the work of a large volume of milk.

Where it comes from: An enzyme that splits lactose into glucose and galactose. It is grown in a fermenter, usually from a fungus such as Kluyveromyces lactis or Aspergillus oryzae, and the harvested enzyme is purified and dried.

Why it’s in food

  • Lactose-free milk
  • Yogurt making
  • Cheese making
  • Dairy supplements
  • Ice cream

Often found in

Lactose-free milkYogurtCheeseIce creamDairy supplements

Also listed as: Lactase, Beta-galactosidase, Lactase enzyme, Beta-galactosidase enzyme, Lactase preparation

Health & gut impact

Enzyme safetyBenefit

EFSA evaluated beta-galactosidase preparations from several sources and found no safety concern at the intended uses, and US GRAS notices for lactase were concluded without questions. Food enzymes are broken down to amino acids in the gut, so there is no residue and no build-up.

EFSA Panel on Food Enzymes, safety evaluation of beta-galactosidase preparations

Allergen carryover in fermentationUnder study

Lactase made with a microorganism grown on a medium containing milk or wheat can carry traces of those proteins. The labels of the commercial preparations declare the substrate, which matters for anyone with a milk or wheat allergy.

EFSA Panel on Food Enzymes, safety evaluation of beta-galactosidase preparations

What can I use instead?

Lactose-free milk

Ratio: Use the same volume in place of ordinary milk

Best for: Drinking and cooking

Hard cheese

Ratio: Replace the milk in the recipe; aged cheese has almost no lactose

Best for: Cooking

Related

More enzymes:

Common questions

Is lactase vegan?

Yes. It is made by fermentation from microorganisms, and the commercial preparations are grown on a plant or mineral medium rather than from an animal source.

Can I take lactase if I am lactose intolerant?

Yes, that is what it is for. Taking it with a meal that contains lactose splits the lactose before it reaches the gut, which is why lactose-free milk works for most people with a mild intolerance.

Is lactase the same as lactase tablets?

The enzyme is the same. The tablets are a food supplement form of it, and the enzyme added to milk in the factory is the same substance used at a much higher dose so that the milk is pre-split.

Is Lactase safe?

Generally safe (90/100). Lactase is generally recognized as safe in the US, with FDA GRAS notices for beta-galactosidase enzyme preparations from several sources. In the EU it is a food enzyme authorized under the food enzymes regulation rather than an additive with an E-number, and it is permitted in Canada for the same purpose.

Is Lactase vegan?

Yes. Made by fermentation, with no animal source.

Spotted a mistake on this page? Report it ›

Scientific sources & regulatory citations
  • EFSA Panel on Food Enzymes, safety evaluation of beta-galactosidase preparations