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E969 Advantame

E969SweetenersOrigin: Lab-made
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The short answer
Advantame (E969) is an extremely intense sweetener related to aspartame. Regulators approve it, and the amount in a food is tiny next to the daily limit. It does not carry aspartame's phenylalanine warning at normal use.
Generally safe

Fine for most people at normal amounts.

E-numberE969
Comes fromLab-made
What it doesSweeteners
Glycemic index—
Daily limit5 mg/kg
Also calledAdvantame

Rules by country

🇺🇸 US FDAApproved
🇪🇺 European UnionApproved
🇨🇦 Health CanadaApproved
CaliforniaNo extra rules

Advantame is an approved high-intensity sweetener in the US, the EU and Canada. EFSA's daily limit is 5 mg per kg of body weight. Because it is so sweet, a serving contains far less than that.

How much is too much? (Acceptable Daily Intake)

350 mgper day is the safe upper limit

Based on 5 mg per kg of body weight (EFSA / JECFA). A 20 kg (44 lb) child: 100 mg a day.

What is it?

A few milligrams of advantame replace a spoon of sugar. Heat does not destroy it as easily as aspartame, so it can go into baked goods. Most people will rarely see it as the only sweetener; it is often blended.

Where it comes from: Advantame is made from aspartame and vanillin. It is thousands of times sweeter than sugar, so foods use only a few milligrams.

Why it’s in food

  • Sweetens drinks in milligrams
  • Sweetens baked goods
  • Blends with other sweeteners
  • Cuts sugar in dairy

Often found in

Soft drinksPowdered drink mixesChewing gumYogurtBaked goodsTabletop blends

Also listed as: Advantame

Health & gut impact

Daily limitConcern

EFSA set advantame's daily limit at 5 mg per kg of body weight. A sweetened drink uses a small slice of that.

EFSA opinion on advantame (2013)

PhenylalanineConcern

Advantame is built from aspartame, but the dose is so low that EFSA did not require the phenylketonuria warning used on aspartame.

EFSA Panel on Food Additives (2013)

What can I use instead?

Stevia

Ratio: To taste

Best for: Drinks

Monk fruit

Ratio: To taste

Best for: Tabletop use

Related

More sweeteners:

Acesulfame Potassium (Ace-K) E950Acesulfame potassium (Ace-K, E950) is a zero-calorie sweetener approved in the US, EU and Canada. EFSA re-checked it in 2025 and raised its daily limit. It's usually paired with sucralose or aspartame to hide a slightly bitter aftertaste.Use in moderationAlluloseAllulose is a "rare sugar" that tastes like sugar but has almost no calories and doesn't raise blood sugar. It's keto-friendly and browns like real sugar in baking.Generally safeAspartame E951Aspartame (E951) is a zero-calorie sweetener in diet soda. It's approved, but WHO's cancer agency called it "possibly carcinogenic" in 2023, and people with PKU must avoid it.Use in moderationCyclamate E952Cyclamate (E952) is a zero-calorie sweetener banned in US food since 1969 and still used in Europe and as a Canadian tabletop sweetener. The ban followed bladder-tumor studies in rats that later reviews judged not to apply cleanly to people.Best to avoid

Common questions

Does advantame need the PKU warning that aspartame does?

No. The amount of phenylalanine it could release in a normal serving is far below aspartame's, and EFSA did not require that warning.

Is Advantame safe?

Generally safe (86/100). Advantame is an approved high-intensity sweetener in the US, the EU and Canada. EFSA's daily limit is 5 mg per kg of body weight. Because it is so sweet, a serving contains far less than that.

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Scientific sources & regulatory citations
  • 21 CFR 172.803 (US FDA)
  • EFSA OpenFoodTox: E969
  • EFSA opinion on advantame (2013)
  • EFSA Panel on Food Additives (2013)

INS 969 · CAS 714229-20-6